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Hot off the press: new data from a collaboration between the BSRC and geneticists in Canada demonstrate the utility of genetics to predict either ASD or atypical development in infant siblings of children already with a diagnosis. Researchers have been trying to develop more precise biological mechanisms to make predictions in these infants, because they have a 15x greater chance of having a diagnosis, they can’t afford a “wait and see” approach. Also, while genetics had originally been thought to be irrelevant to some brain pathology in ASD, it’s now been shown possible that it contributes to the immune hyper activation in the brain. This week, Dr. Matt Anderson from the Autism BrainNet describes “blebs” in the cells of the brain caused by t-lymphocytes. What causes them? Genes? something else? Thank you to Dr. Anderson for joining in this podcast to explain.
https://www.ncbi.nlm.nih.gov/pubmed/31801954
https://www.ncbi.nlm.nih.gov/pubmed/31591744