Get some zzzzzz’s

Sleep is a huge problem in ASD. But is it just “sleep” or can we get more specific? What role do genetics have? And does being autistic make sleep problems worse? Answers come from an unlikely source: mice! Learn more about recent scientific evidence tying sleep problems to ASDs and neurodevelopmental disorders. These include: type of sleep problems autistic people face, why they exist, where they come from, and how mouse models can help solve them.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6639428/

https://www.frontiersin.org/articles/10.3389/fpsyt.2020.559694/full

https://pubmed.ncbi.nlm.nih.gov/30737588/

https://molecularautism.biomedcentral.com/articles/10.1186/s13229-021-00426-w

https://pubmed.ncbi.nlm.nih.gov/33549123/

https://onlinelibrary.wiley.com/doi/10.1002/ajmg.a.62086

Are animal models for ASD a monkey wrench or useful tool?

A new animal model of autism appeared this week:  the monkey.  This adds to the ever growing list of different model systems from autism, from fruit flies to mice and rats now up to monkeys.  Are these animal models useful and for what, and why isn’t there just ONE model of autism rather than the dozen that exist?  This week’s podcast discusses research from scientists at the UC Davis MIND Institute and what they are doing to improve these models of ASD.

https://www.spectrumnews.org/features/multimedia/webinars/webinar-jill-silverman-makes-case-rat-models-autism/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5810939/pdf/nihms906435.pdf

http://news.mit.edu/2019/gene-editing-autism-model-0612