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What’s new in the immune system and ASD

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This holiday weekend always triggers a reincarnation, a resurrection of the vaccine – autism hypothesis.  Many of you have read about the measles epidemics that are hitting many areas of the country.  But besides vaccines, there are other aspects of the immune system that may be linked to autism in some people.  The include family history of autoimmune disorders as well as specific genetic mutations that confer protection against subtypes of ASD.  This week’s ASF podcast will explore these theories and present different ideas on how the immune response is involved in autism, and if it is at all.

https://www.ncbi.nlm.nih.gov/pubmed/30976114 

https://www.ncbi.nlm.nih.gov/pubmed/30975444

 

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That new study on mortality in people with autism…..

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…..may be overestimating the risk of drowning and suffocation in those with ASD.  The study claims a higher rate of drowning and other accidental deaths in people with autism, which is true, but the magnitude of the effect they found was astronomical and misleading given the methodology.  They counted people with autism off of information on their death certificate.  Not everyone with autism has this code listed on their death certificate – so likely this number is underestimated and the risk of drowning overestimated.  The shocking results call for things like swimming lessons in those with autism and other drastic safety measures.  People with autism ARE at a higher risk of drowning and we should all pay attention.   Ways to prevent accidental death in people with autism are needed and the overall message should be the same.  But the numbers themselves are probably a little off.