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Is anxiety related to autism, and where is it in the brain?

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Anxiety is common in people with autism – but is is different than other types of anxiety or similar? Is it part of the autism phenotype? When does it start and what triggers it? Two new studies which use a longitudinal design and examine the links between autism features, anxiety symptoms and brain development are summarized this week. It shows that the amygdala is important, that some features of anxiety are core to ASD and some are separate, and it is related to autism features like insistence on sameness. This has implications for how anxiety is diagnosed and treated in those with ASD.

https://pubmed.ncbi.nlm.nih.gov/35871413/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9116934/?report=printable

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Nobody puts babies in a corner

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Nobody can dispute that research to better understand autistic adolescents and adults is lacking.  However, scientists continue to make important scientific discoveries in infants and toddlers with autism.  These infants and toddlers eventually become adolescents and adults, so identifying critical periods of brain development that influences behavior, what to say to parents and when, and how to  engage the entire community to better serve infants and toddlers is still needed.  This week is an update on the activities of the Baby Siblings Research Consortium (BSRC), including a paper that ties in activity of different brain regions at 1 year olds, to stereotyped behaviors and insistence on sameness in 2 year olds.  The research of the BSRC is directly applicable to families affected by autism at all ages.

 

https://www.ncbi.nlm.nih.gov/pubmed/30446435