Guys, we all need exercise

People with autism are less likely to be physically active and more likely to be sedentary.    A number of studies have looked into different physical activities, both group based and individually, on improvements in health as well as core features of autism, and most have had positive results.  New animal model research demonstrates a benefit of exercise using the maternal immune activation model of ASD, pruning back the excess of connections and cell fibers.  As people with autism also have too many connections in the brain, this may have a direct therapeutic benefit.  But besides all the scientific conjecture, we all need more exercise, physical activity interventions seem to only help, not hurt, people across the spectrum, and should be used to complement, not replace existing therapies.

 

 

https://www.ncbi.nlm.nih.gov/pubmed/29693781

 

https://www.ncbi.nlm.nih.gov/pubmed/31102193

 

https://link.springer.com/article/10.1007%2Fs10803-019-04050-9

 

https://www.cell.com/cell-reports/retrieve/pii/S2211124719306266?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS2211124719306266%3Fshowall%3Dtrue

Regression in autism, down to the neuron

On Friday, February 19, the NIH organized a workshop on regression in autism.  It included autism researchers as well as neurobiologists studying regression in other disorders, specifically Rett Syndrome.  Rett Syndrome is characterized by a regression in symptoms around 18-30 months of age but is the result of a known genetic mutation.  Because the genetic mutation is know, researchers have been able to make huge advancements in the study of the cellular causes of regression.  Do they apply to autism?  The theory of overturning is presented and discussed in the workshop and on the podcast.  You can see the full agenda at:  https://iacc.hhs.gov/non-iacc-events/2016/loss-of-skill-agenda-february19.shtml

Here are some screen shots of the workshop:

 

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