fathers – ASF Weekly Science Podcasts

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On the heels of Father’s Day, this week’s podcast summarizes the last year or so of research which focuses on the fathers. This includes genetics, parental stress and quality of life, and broader autism phenotype features. Of note, two new studies that look at antidepressant exposure in father and probability of having a child with autism – a variation on studying maternal exposures. For anyone interested, here is a list of references used:

https://www.ncbi.nlm.nih.gov/pubmed/28630308

https://www.ncbi.nlm.nih.gov/pubmed/28750543

https://www.ncbi.nlm.nih.gov/pubmed/29884724

https://www.ncbi.nlm.nih.gov/pubmed/25339495

https://www.ncbi.nlm.nih.gov/pubmed/29731598

https://www.ncbi.nlm.nih.gov/pubmed/29478155

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Lots of people tend to think of the genetics of disorders or disease about one mutation or genetic variation that is inherited from the mother or the father, that causes a trait directly. Unfortunately, the genetics of autism isn’t that simple or scientists would have found “the gene” by now. In fact, there are different types of genetic influences in autism. A new study in Nature Genetics led by Elise Robinson shows how common variation influences autism risk, as well as intellectual function in autism, compared to de novo mutations. There is a short primer at the beginning of the podcast about old-school genetic thinking and why it doesn’t apply to ASD. Below is the picture mentioned.

Tag: fathers

A new understanding of autism genetics