More on that Korea Daily mess. Plus early detection of ASD does improve outcomes.

This podcast was going to be dedicated to new early detection research which shows what the USPSTF has been looking for – the link between early detection, early intervention, and improved outcomes in a community setting.  Those findings are still included this week, but there is a slight diversion in theme.  The podcast will also include  an explanation of the immune/microbiome study published in Nature and misrepresented  by Korea Daily.  The study is important, however, the media sensationalized the findings and did the research no favors by labeling it a “major cause”.   Learn what the study did and what it actually discovered in this week’s podcast.

 

Here are the references of the studies mentioned in the podcast:

https://www.ncbi.nlm.nih.gov/pubmed/28902840

https://www.ncbi.nlm.nih.gov/pubmed/28905160

https://www.ncbi.nlm.nih.gov/pubmed/27474118

 

 

Betsy DeVos, autism screening and testosterone – in that order

This week two studies which examined infants and younger children that will significantly advance understanding of causes and services for people with autism were published.  After a commentary about the confirmation of Betsy DeVos, the study that used a practical methodology to improve autism screening in pediatrics clinic from researchers at Duke University was presented.  After that, some early results from the EARLI study  which examined pregnancies in families where an older sibling was diagnosed was presented.  In this study, Bo Park and her colleagues at Drexel University, Johns Hopkins University, University of California at Davis and Kaiser Permanente show that testosterone levels in pregnancy aren’t related to later autism symptoms unless the older sibling affected is a girl.  These findings can illustrate why girls are less likely to be diagnosed with autism compared to boys.  The study is open access and can be downloaded here, thanks to the journal Molecular Autism:  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5282802/pdf/13229_2017_Article_118.pdf

 

13229_2017_118_Fig3_HTML

The importance if IQ in an autism outcome.

Cognitive ability, measured by intellectual quotient or IQ, has been thought to predict response to intervention, social abilities, adaptive behavior and long term outcome.  Numerous studies have shown that it can influence what is labeled as a good outcome.  However, two studies this week point out how those across the spectrum in cognitive ability still benefit from early intervention and make friends on the playground.  In both studies, there were factors that were more important for outcome than IQ.  So it may be an important factor in outcome, but not the only factor.

Old exposures, new diagnoses and more efficient screening for toddlers

This week, two important studies came out on different topics in autism research.  In the first study, an exposure which has been around for decades, PCB’s, a toxic industrial chemical which has been banned from manufacture or use for the past few decades, was linked to autism.  This dispels the myth that only exposures that have been introduced since the observance in the rise in diagnoses are relevant for study.  First author Kristen Lyall gives her perspective. Here is a website on how to avoid PCBs even though they have been banned.

Second, screening for autism in pediatricians offices has always been challenging.  Patients get 10 minutes at most with their doctor, these doctors have to fit in an hours worth of assessments in this time.  So how can you get them to conduct a screening for autism and add in extra questions?  Kennedy Krieger Institute published on a way that seems to work without sacrificing quality.  Hear more about both on this week’s podcast.